I don't know what it is...but for some reason, despite understanding and seeing why your jokes would be funny... your nine latest comics, plus the one I found you with, but wow, just none of them are funny to me at all. I'm not sure if the art style bugs me or it's something about your timing or what, but it doesn't work. Obviously working for others though, so keep up the good work.
I think everyone here is forgetting, Two Guys and Guy is about 3 terrible people. One violent, manipulative sadist, one genocidal, sociopathic madman, and one plain ol' jerk (and arguably all of his clones). Wayne only seems nice by comparison. It's the trifecta that we've all come to love.
That being said, that nerd is lying to you Wayne. You also have to remember to mark her door with ox blood. THEN, you're in the clear.